Mevalonate Kinase (MVK) Peptid
MVK
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN939705
Kurzübersicht für Mevalonate Kinase (MVK) Peptid (ABIN939705)
Target
MVK
(Mevalonate Kinase (MVK))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- KEDLELINKW AFQGERMIHG NPSGVDNAVS TWGGALRYHQ GKISSLKRSP
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of MVK antibody,
Alternative Names: MVK control peptide, MVK antibody Blocking Peptide, Anti-MVK Blocking Peptide, Mevalonate Kinase Blocking Peptide, LRBP Blocking Peptide, MVLK Blocking Peptide -
Aufreinigung
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- MVK (Mevalonate Kinase (MVK))
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Hintergrund
- MVK is the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash.
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Molekulargewicht
- 42 kDa
Target
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