Transcription Factor MafK (MAFK) Peptid
MAFK
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
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- Target Alle MAFK Produkte
- MAFK (Transcription Factor MafK (MAFK))
- Protein-Typ
- Synthetic
- Spezies
- Säugetier
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- KEAGENAPVL SDDELVSMSV RELNQHLRGL TKEEVTRLKQ RRRTLKNRGY
- Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of MAFK antibody,
Alternative Names: MAFK control peptide, MAFK antibody Blocking Peptide, Anti-MAFK Blocking Peptide, v-maf musculoaponeurotic fibrosarcoma oncogene homolog K, avian Blocking Peptide, FLJ32205 Blocking Peptide, MGC71717 Blocking Peptide, NFE2U Blocking Peptide, P18 Blocking Peptide
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- Applikationshinweise
- Optimal conditions should be determined by the investigator
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C long term.
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- Target
- MAFK (Transcription Factor MafK (MAFK))
- Hintergrund
- The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2. NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, PBGD and FECH. NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG, or MafK) and p45. Both subunits are members of the activator protein-1 superfamily of bZIP proteins. Maf homodimers suppress transcription at NFE2 sites.
- Molekulargewicht
- 17 kDa
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