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Fc Fragment of IgE Receptor Ia (FCER1A) Peptid

FCER1A Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN939615

Kurzübersicht für Fc Fragment of IgE Receptor Ia (FCER1A) Peptid (ABIN939615)

Target

Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))

Spezies

Säugetier

Quelle

  • 5
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    IYYKDGEALK YWYENHNISI TNATVEDSGT YYCTGKVWQL DYESEPLNIT

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of FCER1 A antibody,
    Alternative Names: FCER1A control peptide, FCER1A antibody Blocking Peptide, Anti-FCER1A Blocking Peptide, Fc Fragment Of Ige High Affinity I Receptor For, Alpha Polypeptide Blocking Peptide, FCE1A Blocking Peptide, FcERI Blocking Peptide, FCER1A, FCERA-1, FCERA 1, FCERA-1 Blocking Peptide, FCERA 1 Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))

    Hintergrund

    The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response.

    Molekulargewicht

    27 kDa
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