Metalloproteinase Inhibitor 2 (TIMP2) Peptid
TIMP2
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN939590
Kurzübersicht für Metalloproteinase Inhibitor 2 (TIMP2) Peptid (ABIN939590)
Target
TIMP2
(Metalloproteinase Inhibitor 2 (TIMP2))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- IVPWDTLSTT QKKSLNHRYQ MGCECKITRC PMIPCYISSP DECLWMDWVT
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of TIMP2 antibody,
Alternative Names: TIMP2 control peptide, TIMP2 antibody Blocking Peptide, Anti-TIMP2 Blocking Peptide, TIMP metallopeptidase inhibitor 2 Blocking Peptide, CSC-21K Blocking Peptide, TIMP2, TIMP-2, TIMP 2, TIMP-2 Blocking Peptide, TIMP 2 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
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Hintergrund
- This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
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Molekulargewicht
- 22 kDa
Target
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