A synthetic peptide for use as a blocking control in assays to test for specificity of ACER1 antibody, Alternative Names: ACER1 control peptide, ACER1 antibody Blocking Peptide, Anti-ACER1 Blocking Peptide, alkaline ceramidase 1 Blocking Peptide, ASAH3 Blocking Peptide, MGC138327 Blocking Peptide, MGC138329 Blocking Peptide, ACER1, ACER-1, ACER 1, ACER-1 Blocking Peptide, ACER 1 Blocking Peptide
ACER1
Reaktivität: Human, Affe, Maus, Ratte
Wirt: Synthetic
BP
Applikationshinweise
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
ACER1
(Alkaline Ceramidase 1 (ACER1))
Hintergrund
ACER1 hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. It has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. It may have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids.