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Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3) Peptid

KCNN3 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN939558
  • Target Alle KCNN3 Produkte
    KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    ITELNDRSED LEKQIGSLES KLEHLTASFN SLPLLIADTL RQQQQQLLSA
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of KCNN3 antibody,
    Alternative Names: KCNN3 control peptide, KCNN3 antibody Blocking Peptide, Anti-KCNN3 Blocking Peptide, Potassium Intermediate/Small Conductance Calcium-Activated Channel Subfamily N Member 3 Blocking Peptide, KCNN3, KCNN-3, KCNN 3, KCNN-3 Blocking Peptide, KCNN 3 Blocking Peptide
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
    Synonyme
    KCa2.3 Peptide, SK3 Peptide, SKCA3 Peptide, hSK3 Peptide, potassium calcium-activated channel subfamily N member 3 Peptide, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 Peptide, Kcnn3 Peptide, KCNN3 Peptide
    Hintergrund
    Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.
    Molekulargewicht
    81 kDa
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