A synthetic peptide for use as a blocking control in assays to test for specificity of SSB antibody, Alternative Names: SSB control peptide, SSB antibody Blocking Peptide, Anti-SSB Blocking Peptide, Sjogren Syndrome Antigen B Blocking Peptide, Autoantigen La Blocking Peptide, LARP3 Blocking Peptide, La Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
SSB
(Sjogren Syndrome Antigen B (SSB))
Hintergrund
SSB is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. SSB protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.