A synthetic peptide for use as a blocking control in assays to test for specificity of TCAP antibody, Alternative Names: TCAP control peptide, TCAP antibody Blocking Peptide, Anti-TCAP Blocking Peptide, Titin-Cap Blocking Peptide, Telethonin Blocking Peptide, CMD1N Blocking Peptide, LGMD2G Blocking Peptide, T-cap Blocking Peptide, TELE Blocking Peptide, telethonin Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
TCAP
(Titin-Cap (Telethonin) (TCAP))
Hintergrund
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.