Trichoplein, Keratin Filament Binding (TCHP) Peptid
Kurzübersicht für Trichoplein, Keratin Filament Binding (TCHP) Peptid (ABIN939497)
Target
Spezies
Quelle
Applikation
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Protein-Typ
- Synthetic
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Sequenz
- IQEKIEQNRR AQEESLKHRE QLIRNLEEVR ELARREKEES EKLKSARKQE
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of TCHP antibody,
Alternative Names: TCHP control peptide, TCHP antibody Blocking Peptide, Anti-TCHP Blocking Peptide, trichoplein, keratin filament binding Blocking Peptide, MGC10854 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
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Hintergrund
- TCHP is a tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. It inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. It may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. And it also may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
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Molekulargewicht
- 61 kDa
Target
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