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Trichoplein, Keratin Filament Binding (TCHP) Peptid

TCHP Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN939497
  • Target Alle TCHP Produkte
    TCHP (Trichoplein, Keratin Filament Binding (TCHP))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    IQEKIEQNRR AQEESLKHRE QLIRNLEEVR ELARREKEES EKLKSARKQE
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of TCHP antibody,
    Alternative Names: TCHP control peptide, TCHP antibody Blocking Peptide, Anti-TCHP Blocking Peptide, trichoplein, keratin filament binding Blocking Peptide, MGC10854 Blocking Peptide
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    TCHP (Trichoplein, Keratin Filament Binding (TCHP))
    Hintergrund
    TCHP is a tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. It inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. It may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. And it also may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
    Molekulargewicht
    61 kDa
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