Trichoplein, Keratin Filament Binding (TCHP) Peptid
TCHP
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN939497
Kurzübersicht für Trichoplein, Keratin Filament Binding (TCHP) Peptid (ABIN939497)
Target
TCHP
(Trichoplein, Keratin Filament Binding (TCHP))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- IQEKIEQNRR AQEESLKHRE QLIRNLEEVR ELARREKEES EKLKSARKQE
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of TCHP antibody,
Alternative Names: TCHP control peptide, TCHP antibody Blocking Peptide, Anti-TCHP Blocking Peptide, trichoplein, keratin filament binding Blocking Peptide, MGC10854 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
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Hintergrund
- TCHP is a tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. It inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. It may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. And it also may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
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Molekulargewicht
- 61 kDa
Target
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