Trichoplein, Keratin Filament Binding (TCHP) Peptid
TCHP
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
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- Target Alle TCHP Produkte
- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
- Protein-Typ
- Synthetic
- Spezies
- Säugetier
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- IQEKIEQNRR AQEESLKHRE QLIRNLEEVR ELARREKEES EKLKSARKQE
- Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of TCHP antibody,
Alternative Names: TCHP control peptide, TCHP antibody Blocking Peptide, Anti-TCHP Blocking Peptide, trichoplein, keratin filament binding Blocking Peptide, MGC10854 Blocking Peptide
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- Applikationshinweise
- Optimal conditions should be determined by the investigator
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C long term.
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- Target
- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
- Hintergrund
- TCHP is a tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. It inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. It may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. And it also may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
- Molekulargewicht
- 61 kDa
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