4-Aminobutyrate Aminotransferase (ABAT) Peptid
ABAT
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN939395
Kurzübersicht für 4-Aminobutyrate Aminotransferase (ABAT) Peptid (ABIN939395)
Target
ABAT
(4-Aminobutyrate Aminotransferase (ABAT))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- IIVEPIQSEG GDNHASDDFF RKLRDIARKH GCAFLVDEVQ TGGGCTGKFW
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of ABAT antibody,
Alternative Names: ABAT control peptide, ABAT antibody Blocking Peptide, Anti-ABAT Blocking Peptide, 4-Aminobutyrate Aminotransferase Blocking Peptide, GABA-AT Blocking Peptide, GABAT Blocking Peptide, NPD009 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- ABAT (4-Aminobutyrate Aminotransferase (ABAT))
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Hintergrund
- 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50 kDa subunits complexed to pyridoxal-5-phosphate. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde.
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Molekulargewicht
- 55 kDa
Target
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