A synthetic peptide for use as a blocking control in assays to test for specificity of INPP5 B antibody, Alternative Names: INPP5B control peptide, INPP5B antibody Blocking Peptide, Anti-INPP5B Blocking Peptide, Inositol Polyphosphate-5-Phosphatase 75Kda Blocking Peptide, 5PTase Blocking Peptide, MGC65156 Blocking Peptide, MGC71303 Blocking Peptide, INPP5B, INPPB-5, INPPB 5, INPPB-5 Blocking Peptide, INPPB 5 Blocking Peptide
Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B is the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus.