A synthetic peptide for use as a blocking control in assays to test for specificity of RNF19 A antibody, Alternative Names: RNF19A control peptide, RNF19A antibody Blocking Peptide, Anti-RNF19A Blocking Peptide, Ring Finger Protein 19A Blocking Peptide, DKFZp566B1346 Blocking Peptide, DORFIN Blocking Peptide, RNF19 Blocking Peptide, RNF19, RNF-19, RNF 19, RNF-19 Blocking Peptide, RNF 19 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
RNF19A
(Ring Finger Protein 19A (RNF19A))
Synonyme
RNF19 Peptide, RNF19A Peptide, AA032313 Peptide, Dorfin Peptide, Rnf19 Peptide, UIP117 Peptide, Ubce7ip2 Peptide, XYbp Peptide, ring finger protein 19A, RBR E3 ubiquitin protein ligase Peptide, ring finger protein 19A Peptide, RNF19A Peptide, Rnf19a Peptide
Hintergrund
RNF19A contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB.