A synthetic peptide for use as a blocking control in assays to test for specificity of POLR3 B antibody, Alternative Names: POLR3B control peptide, POLR3B antibody Blocking Peptide, Anti-POLR3B Blocking Peptide, RNA Polymerase IIIB Blocking Peptide, FLJ10388 Blocking Peptide, RPC2 Blocking Peptide, POLR3B, POLRB-3, POLRB 3, POLRB-3 Blocking Peptide, POLRB 3 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
POLR3B
(Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))
Synonyme
RGD1565311 Peptide, C128 Peptide, HLD8 Peptide, RPC2 Peptide, 2700078H01Rik Peptide, A330032P03Rik Peptide, C85372 Peptide, RNA polymerase III subunit B Peptide, polymerase (RNA) III (DNA directed) polypeptide B Peptide, Polr3b Peptide, POLR3B Peptide
Hintergrund
POLR3B belongs to the RNA polymerase beta chain family. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR3B is the second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.