A synthetic peptide for use as a blocking control in assays to test for specificity of PCDH15 antibody, Alternative Names: PCDH15 control peptide, PCDH15 antibody Blocking Peptide, Anti-PCDH15 Blocking Peptide, Protocadherin 15 Blocking Peptide, RP11-449J3.2 Blocking Peptide, DFNB23 Blocking Peptide, DKFZp667A1711 Blocking Peptide, USH1F Blocking Peptide, PCDH15, PCDH-15, PCDH 15, PCDH-15 Blocking Peptide, PCDH 15 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
PCDH15
(Protocadherin-15 (PCDH15))
Hintergrund
PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.