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Synovial Sarcoma, X Breakpoint 2 (SSX2) Peptid

SSX2 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN939235

Kurzübersicht für Synovial Sarcoma, X Breakpoint 2 (SSX2) Peptid (ABIN939235)

Target

SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

Spezies

Säugetier

Quelle

  • 2
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    HRWSSQNTHN IGRFSLSTSM GAVHGTPKTI THNRDPKGGN MPGPTDCVRE

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of SSX2 antibody,
    Alternative Names: SSX2 control peptide, SSX2 antibody Blocking Peptide, Anti-SSX2 Blocking Peptide, synovial sarcoma, X breakpoint 2 Blocking Peptide, HD21 Blocking Peptide, HOM-MEL-40 Blocking Peptide, MGC119055 Blocking Peptide, MGC15364 Blocking Peptide, MGC3884 Blocking Peptide, SSX Blocking Peptide, SSX2, SSX-2, SSX 2, SSX-2 Blocking Peptide, SSX 2 Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

    Hintergrund

    SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

    Molekulargewicht

    25 kDa
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