A synthetic peptide for use as a blocking control in assays to test for specificity of MRPL10 antibody, Alternative Names: MRPL10 control peptide, MRPL10 antibody Blocking Peptide, Anti-MRPL10 Blocking Peptide, Mitochondrial Ribosomal Protein L10 Blocking Peptide, MGC17973 Blocking Peptide, MRP-L8 Blocking Peptide, RPML8 Blocking Peptide, MRPL10, MRPL-10, MRPL 10, MRPL-10 Blocking Peptide, MRPL 10 Blocking Peptide
Aufreinigung
The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
MRPL10
(Mitochondrial Ribosomal Protein L10 (MRPL10))
Hintergrund
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 5q.