A synthetic peptide for use as a blocking control in assays to test for specificity of MAP4 K2 antibody, Alternative Names: MAP4K2 control peptide, MAP4K2 antibody Blocking Peptide, Anti-MAP4K2 Blocking Peptide, Mitogen-Activated Protein Kinase 2 Blocking Peptide, BL44 Blocking Peptide, GCK Blocking Peptide, RAB8IP Blocking Peptide, MAP4, MAP-4, MAP 4, MAP-4 Blocking Peptide, MAP 4 Blocking Peptide
MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.