FYVE, RhoGEF and PH Domain Containing 1 (FGD1) Peptid
FGD1
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN939123
Kurzübersicht für FYVE, RhoGEF and PH Domain Containing 1 (FGD1) Peptid (ABIN939123)
Target
FGD1
(FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- HGHRAPGGAG PSEPEHPATN PPGAAPPACA DSDPGASEPG LLARRGSGSA
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of FGD1 antibody,
Alternative Names: FGD1 control peptide, FGD1 antibody Blocking Peptide, Anti-FGD1 Blocking Peptide, FYVE, RhoGEF and PH domain containing 1, faciogenital dysplasia Blocking Peptide, AAS Blocking Peptide, FGDY Blocking Peptide, ZFYVE3 Blocking Peptide, FGD1, FGD-1, FGD 1, FGD-1 Blocking Peptide, FGD 1 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
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Hintergrund
- FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs.
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Molekulargewicht
- 106 kDa
Target
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