A synthetic peptide for use as a blocking control in assays to test for specificity of SILV antibody, Alternative Names: SILV control peptide, SILV antibody Blocking Peptide, Anti-SILV Blocking Peptide, Silver Homolog Blocking Peptide, D12S53E Blocking Peptide, ME20 Blocking Peptide, PMEL17 Blocking Peptide, SI Blocking Peptide, SIL Blocking Peptide, gp100 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
Melanoma gp100 (PMEL)
(Premelanosome Protein (PMEL))
Hintergrund
SILV could be a melanogenic enzyme. It could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, it could protect tumor cells from antibody mediated immunity.