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Premelanosome Protein (PMEL) Peptid

PMEL Reaktivität: Säugetier Wirt: Synthetic BP, IHC, WB
Produktnummer ABIN939113

Kurzübersicht für Premelanosome Protein (PMEL) Peptid (ABIN939113)

Target

Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Spezies

Säugetier

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
  • Protein-Typ

    Synthetic

    Sequenz

    HFLRNQPLTF ALQLHDPSGY LAEADLSYTW DFGDSSGTLI SRALVVTHTY

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of SILV antibody,
    Alternative Names: SILV control peptide, SILV antibody Blocking Peptide, Anti-SILV Blocking Peptide, Silver Homolog Blocking Peptide, D12S53E Blocking Peptide, ME20 Blocking Peptide, PMEL17 Blocking Peptide, SI Blocking Peptide, SIL Blocking Peptide, gp100 Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

    Hintergrund

    SILV could be a melanogenic enzyme. It could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, it could protect tumor cells from antibody mediated immunity.

    Molekulargewicht

    70 kDa
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