Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8) Peptid
SMG8
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN939088
382,12 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 20 bis 27 Werktagen
Kurzübersicht für Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8) Peptid (ABIN939088)
Target
SMG8
(Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
-
-
Protein-Typ
- Synthetic
-
Sequenz
- HCVHKFHSLP KSGEKPEADR NPPVLYHNSR ARSTGACNCG RKQAPRDDPF
-
Produktmerkmale
-
A synthetic peptide for use as a blocking control in assays to test for specificity of C17 orf71 antibody,
Alternative Names: C17ORF71 control peptide, C17ORF71 antibody Blocking Peptide, Anti-C17ORF71 Blocking Peptide, FLJ10587 Blocking Peptide
-
-
-
-
Applikationshinweise
- Optimal conditions should be determined by the investigator
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
-
Buffer
- PBS
-
Handhabung
- Avoid repeated freeze/thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20 °C long term.
-
-
- SMG8 (Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
-
Hintergrund
- The C17ORF71 protein is a component of the SMG1C complex, a mRNA surveillance complex that recognises and degrades mRNAs containing premature translation termination codons (PTCs) via the nonsense-mediated mRNA decay (NMD). The complex probably acts by associating with ribosomes during tranlation termination on mRNPs. If an exon junction complex (EJC) is located 50-55 or more nucleotides downstream from the termination codon, SMG1 phosphorylates UPF1/RENT1, triggering nonsense-mediated mRNA decay (NMD).
-
Molekulargewicht
- 110 kDa
Target
-
Sie sind hier:
