Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8) Peptid
SMG8
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN939088
Kurzübersicht für Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8) Peptid (ABIN939088)
Target
SMG8
(Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- HCVHKFHSLP KSGEKPEADR NPPVLYHNSR ARSTGACNCG RKQAPRDDPF
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of C17 orf71 antibody,
Alternative Names: C17ORF71 control peptide, C17ORF71 antibody Blocking Peptide, Anti-C17ORF71 Blocking Peptide, FLJ10587 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- SMG8 (Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
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Hintergrund
- The C17ORF71 protein is a component of the SMG1C complex, a mRNA surveillance complex that recognises and degrades mRNAs containing premature translation termination codons (PTCs) via the nonsense-mediated mRNA decay (NMD). The complex probably acts by associating with ribosomes during tranlation termination on mRNPs. If an exon junction complex (EJC) is located 50-55 or more nucleotides downstream from the termination codon, SMG1 phosphorylates UPF1/RENT1, triggering nonsense-mediated mRNA decay (NMD).
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Molekulargewicht
- 110 kDa
Target
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