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2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) Peptid

OAS1 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN939056

Kurzübersicht für 2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) Peptid (ABIN939056)

Target

OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))

Spezies

Säugetier

Quelle

  • 9
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    GWRQLAQEAE AWLNYPCFKN WDGSPVSSWI LLVRPPASSL PFIPAPLHEA

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of OAS1 antibody,
    Alternative Names: OAS1 control peptide, OAS1 antibody Blocking Peptide, Anti-OAS1 Blocking Peptide, 2'5'-Oligoadenylate Synthetase 1 40/46Kda Blocking Peptide, IFI-4 Blocking Peptide, OIAS Blocking Peptide, OIASI Blocking Peptide, OAS1, OAS-1, OAS 1, OAS-1 Blocking Peptide, OAS 1 Blocking Peptide

    Aufreinigung

    Protein G affinity purified immunoglobulin
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))

    Hintergrund

    OAS1 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Mutations in this gene have been associated with host susceptibility to viral infection.

    Molekulargewicht

    42 kDa
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