A synthetic peptide for use as a blocking control in assays to test for specificity of SNUPN antibody, Alternative Names: SNUPN control peptide, SNUPN antibody Blocking Peptide, Anti-SNUPN Blocking Peptide, Snurportin 1 Blocking Peptide, KPNBL Blocking Peptide, RNUT1 Blocking Peptide, Snurportin1 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
Snurportin 1 (SNUPN)
Hintergrund
The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. SNUPN interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor.