Vacuolar-sorting Protein SNF8 (SNF8) Peptid
SNF8
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN939010
Kurzübersicht für Vacuolar-sorting Protein SNF8 (SNF8) Peptid (ABIN939010)
Target
SNF8
(Vacuolar-sorting Protein SNF8 (SNF8))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- GTVLAEDQLA QMSKQLDMFK TNLEEFASKH KQEIRKNPEF RVQFQDMCAT
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of Snf8 antibody,
Alternative Names: Snf8 control peptide, Snf8 antibody Blocking Peptide, Anti-Snf8 Blocking Peptide, SNF8, ESCRT-II complex subunit, homolog, S. cerevisiae Blocking Peptide, D11moh34 Blocking Peptide, MGC105799 Blocking Peptide, RGD1310144 Blocking Peptide, Snf8, Snf-8, Snf 8, Snf-8 Blocking Peptide, Snf 8 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
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Hintergrund
- Snf8 is required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is a component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL.
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Molekulargewicht
- 28 kDa
Target
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