A synthetic peptide for use as a blocking control in assays to test for specificity of NXT1 antibody, Alternative Names: NXT1 control peptide, NXT1 antibody Blocking Peptide, Anti-NXT1 Blocking Peptide, NTF2-like export factor 1 Blocking Peptide, MTR2 Blocking Peptide, P15 Blocking Peptide, NXT1, NXT-1, NXT 1, NXT-1 Blocking Peptide, NXT 1 Blocking Peptide
The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.