A synthetic peptide for use as a blocking control in assays to test for specificity of THEX1 antibody, Alternative Names: THEX1 control peptide, THEX1 antibody Blocking Peptide, Anti-THEX1 Blocking Peptide, Three Prime Histone mRNA Exonuclease 1 Blocking Peptide, THEX1, THEX-1, THEX 1, THEX-1 Blocking Peptide, THEX 1 Blocking Peptide
THEX1 contains 1 SAP domain and 1 exonuclease domain. It is an RNA exonuclease that binds to the 3' end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. It is also able to degrade the 3' overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi).