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Interleukin 10 Receptor, alpha (IL10RA) Peptid

IL10RA Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN938981

Kurzübersicht für Interleukin 10 Receptor, alpha (IL10RA) Peptid (ABIN938981)

Target

IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Spezies

Säugetier

Quelle

  • 2
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    GSVNLEIHNG FILGKIQLPR PKMAPANDTY ESIFSHFREY EIAIRKVPGN

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of IL10 RA antibody,
    Alternative Names: IL10R Alpha control peptide, IL10R Alpha antibody Blocking Peptide, Anti-IL10R Alpha Blocking Peptide, Interleukin 10 Receptor Alpha Blocking Peptide, CDW210A Blocking Peptide, HIL-10R Blocking Peptide, IL-10R1 Blocking Peptide, IL10R Blocking Peptide, IL10RA Blocking Peptide, IL10, IL-10, IL 10, IL-10 Blocking Peptide, IL 10 Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

    Hintergrund

    IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.

    Molekulargewicht

    61 kDa
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