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Interleukin 10 Receptor, alpha (IL10RA) Peptid

IL10RA Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN938981
  • Target Alle IL-10RA (IL10RA) Produkte
    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 2
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    GSVNLEIHNG FILGKIQLPR PKMAPANDTY ESIFSHFREY EIAIRKVPGN
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of IL10 RA antibody,
    Alternative Names: IL10R Alpha control peptide, IL10R Alpha antibody Blocking Peptide, Anti-IL10R Alpha Blocking Peptide, Interleukin 10 Receptor Alpha Blocking Peptide, CDW210A Blocking Peptide, HIL-10R Blocking Peptide, IL-10R1 Blocking Peptide, IL10R Blocking Peptide, IL10RA Blocking Peptide, IL10, IL-10, IL 10, IL-10 Blocking Peptide, IL 10 Blocking Peptide
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
    Hintergrund
    IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.
    Molekulargewicht
    61 kDa
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