N-Acylaminoacyl-Peptide Hydrolase (APEH) Peptid
APEH
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN938976
Kurzübersicht für N-Acylaminoacyl-Peptide Hydrolase (APEH) Peptid (ABIN938976)
Target
APEH
(N-Acylaminoacyl-Peptide Hydrolase (APEH))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- GSTGFGQDSI LSLPGNVGHQ DVKDVQFAVE QVLQEEHFDA SHVALMGGSH
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of APEH antibody,
Alternative Names: APEH control peptide, APEH antibody Blocking Peptide, Anti-APEH Blocking Peptide, N-Acylaminoacyl-Peptide Hydrolase Blocking Peptide, ACPH Blocking Peptide, APH Blocking Peptide, D3F15S2 Blocking Peptide, D3S48E Blocking Peptide, DNF15S2 Blocking Peptide, MGC2178 Blocking Peptide, OPH Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))
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Hintergrund
- APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
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Molekulargewicht
- 81 kDa
Target
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