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Coagulation Factor VIII (F8) Peptid

F8 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN938955
  • Target Alle Factor VIII (F8) Produkte
    Factor VIII (F8) (Coagulation Factor VIII (F8))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    GSKGEKGERG RAGELGEAGP SGEPGVPGDA GMPGERGEAG HRGSAGALGP
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of F8 antibody,
    Alternative Names: F8 control peptide, F8 antibody Blocking Peptide, Anti-F8 Blocking Peptide, coagulation factor VIII, procoagulant component Blocking Peptide, AHF Blocking Peptide, DXS1253E Blocking Peptide, F8B Blocking Peptide, F8C Blocking Peptide, FVIII Blocking Peptide, HEMA Blocking Peptide, F8, F-8, F 8, F-8 Blocking Peptide, F 8 Blocking Peptide
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    Factor VIII (F8) (Coagulation Factor VIII (F8))
    Synonyme
    fb61d02 Peptide, wu:fb61d02 Peptide, Cf-8 Peptide, Cf8 Peptide, FVIII Peptide, AHF Peptide, DXS1253E Peptide, F8B Peptide, F8C Peptide, HEMA Peptide, coagulation factor VIIi Peptide, coagulation factor VIII Peptide, coagulation factor VIII, procoagulant component Peptide, f7i Peptide, F8 Peptide
    Hintergrund
    This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
    Molekulargewicht
    63 kDa
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