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Coagulation Factor VIII (F8) Peptid

F8 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN938955
382,12 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 20 bis 27 Werktagen

Kurzübersicht für Coagulation Factor VIII (F8) Peptid (ABIN938955)

Target

Factor VIII (F8) (Coagulation Factor VIII (F8))

Spezies

Säugetier

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    GSKGEKGERG RAGELGEAGP SGEPGVPGDA GMPGERGEAG HRGSAGALGP

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of F8 antibody,
    Alternative Names: F8 control peptide, F8 antibody Blocking Peptide, Anti-F8 Blocking Peptide, coagulation factor VIII, procoagulant component Blocking Peptide, AHF Blocking Peptide, DXS1253E Blocking Peptide, F8B Blocking Peptide, F8C Blocking Peptide, FVIII Blocking Peptide, HEMA Blocking Peptide, F8, F-8, F 8, F-8 Blocking Peptide, F 8 Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    Factor VIII (F8) (Coagulation Factor VIII (F8))

    Hintergrund

    This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

    Molekulargewicht

    63 kDa
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