A synthetic peptide for use as a blocking control in assays to test for specificity of CMAS antibody, Alternative Names: CMAS control peptide, CMAS antibody Blocking Peptide, Anti-CMAS Blocking Peptide, Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase Blocking Peptide
CMAS is an enzyme that catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.