A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF259 antibody, Alternative Names: ZNF259 control peptide, ZNF259 antibody Blocking Peptide, Anti-ZNF259 Blocking Peptide, zinc finger protein 259 Blocking Peptide, ZNF259, ZNF-259, ZNF 259, ZNF-259 Blocking Peptide, ZNF 259 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
ZNF259 (znf259)
(Zinc Finger Protein 259 (znf259))
Hintergrund
ZNF259 may be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus. ZNF259 binds to the EGFR and is released from the receptor after activation.ZNF259 is essential for cell viability and its interaction with eEF-1alpha contributes to normal cellular proliferation.ZNF259 translocates from the cytoplasm to the nucleus after treatment of cells with mitogens. ZNF259 accumulates in the nucleolus of proliferating cells. Loss of ZNF259 caused disruption of nucleolar function, including preribosomal RNA expression. ZNF259 is an essential protein that is required for normal nucleolar function in proliferating cells.