A synthetic peptide for use as a blocking control in assays to test for specificity of FZD4 antibody, Alternative Names: FZD4 control peptide, FZD4 antibody Blocking Peptide, Anti-FZD4 Blocking Peptide, Frizzled Homolog 4 Blocking Peptide, EVR1 Blocking Peptide, FEVR Blocking Peptide, FZD4S Blocking Peptide, Fz-4 Blocking Peptide, FzE4 Blocking Peptide, GPCR Blocking Peptide, MGC34390 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
FZD4
(Frizzled Family Receptor 4 (FZD4))
Hintergrund
FZD4 is a member of the frizzled family. Members of this family are seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.