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Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Peptid

CASP4 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN938719

Kurzübersicht für Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Peptid (ABIN938719)

Target

Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Spezies

Säugetier

Quelle

  • 8
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    GILEGICGTV HDEKKPDVLL YDTIFQIFNN RNCLSLKDKP KVIIVQACRG

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of CASP4 antibody,
    Alternative Names: CASP4 control peptide, CASP4 antibody Blocking Peptide, Anti-CASP4 Blocking Peptide, caspase 4, apoptosis-related cysteine peptidase Blocking Peptide, ICE(rel)II Blocking Peptide, ICEREL-II Blocking Peptide, ICH-2 Blocking Peptide, Mih1/TX Blocking Peptide, TX Blocking Peptide, CASP4, CASP-4, CASP 4, CASP-4 Blocking Peptide, CASP 4 Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

    Hintergrund

    This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

    Molekulargewicht

    10 kDa
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