A synthetic peptide for use as a blocking control in assays to test for specificity of ACAT1 antibody, Alternative Names: ACAT1 control peptide, ACAT1 antibody Blocking Peptide, Anti-ACAT1 Blocking Peptide, Acetyl-Coenzyme A Acetyltransferase 1 Blocking Peptide, ACAT Blocking Peptide, MAT Blocking Peptide, T2 Blocking Peptide, THIL Blocking Peptide, ACAT1, ACAT-1, ACAT 1, ACAT-1 Blocking Peptide, ACAT 1 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
ACAT1
(Acetyl-CoA Acetyltransferase 1 (ACAT1))
Hintergrund
ACAT1 is a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. The gene encoding ACAT1 spans approximately 27 kb and contains 12 exons interrupted by 11 introns. Defects in this gene are associated with the alpha-methylacetoaceticaciduria disorder, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.