A synthetic peptide for use as a blocking control in assays to test for specificity of PLP1 antibody, Alternative Names: PLP1 control peptide, PLP1 antibody Blocking Peptide, Anti-PLP1 Blocking Peptide, Proteolipid Protein 1 Blocking Peptide, Pelizaeus-Merzbacher Disease Spastic Paraplegia 2 Uncomplicated Blocking Peptide, MMPL Blocking Peptide, PLP Blocking Peptide, PLP/DM20 Blocking Peptide, PMD Blocking Peptide, SPG2 Blocking Peptide, PLP1, PLP-1, PLP 1, PLP-1 Blocking Peptide, PLP 1 Blocking Peptide
PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.