Fibrillarin (FBL) Peptid
FBL
Reaktivität: Säugetier
Wirt: Synthetic
BP, IHC, WB
Produktnummer ABIN938665
Kurzübersicht für Fibrillarin (FBL) Peptid (ABIN938665)
Target
Fibrillarin (FBL)
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Protein-Typ
- Synthetic
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Sequenz
- GGGFHSGGNR GRGRGGKRGN QSGKNVMVEP HRHEGVFICR GKEDALVTKN
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of FBL antibody,
Alternative Names: Fibrillarin control peptide, Fibrillarin antibody Blocking Peptide, Anti-Fibrillarin Blocking Peptide, FBL Blocking Peptide, Nop1p Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- Fibrillarin (FBL)
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Hintergrund
- FBL is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. FBL contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognise fibrillarin.
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Molekulargewicht
- 35 kDa
Target
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