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Fibrillarin (FBL) Peptid

FBL Reaktivität: Säugetier Wirt: Synthetic BP, IHC, WB
Produktnummer ABIN938665
  • Target Alle Fibrillarin (FBL) Produkte
    Fibrillarin (FBL)
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Sequenz
    GGGFHSGGNR GRGRGGKRGN QSGKNVMVEP HRHEGVFICR GKEDALVTKN
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of FBL antibody,
    Alternative Names: Fibrillarin control peptide, Fibrillarin antibody Blocking Peptide, Anti-Fibrillarin Blocking Peptide, FBL Blocking Peptide, Nop1p Blocking Peptide
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    Fibrillarin (FBL)
    Hintergrund
    FBL is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. FBL contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognise fibrillarin.
    Molekulargewicht
    35 kDa
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