A synthetic peptide for use as a blocking control in assays to test for specificity of TAPBP antibody, Alternative Names: TAPBP control peptide, TAPBP antibody Blocking Peptide, Anti-TAPBP Blocking Peptide, Tap Binding Protein Blocking Peptide, Tapasin Blocking Peptide, NGS17 Blocking Peptide, TAPA Blocking Peptide, TPN Blocking Peptide, TPSN Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
TAPBP
(TAP Binding Protein (Tapasin) (TAPBP))
Hintergrund
TAPBP is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum.