A synthetic peptide for use as a blocking control in assays to test for specificity of LBR antibody, Alternative Names: Lamin B Receptor control peptide, Lamin B Receptor antibody Blocking Peptide, Anti-Lamin B Receptor Blocking Peptide, DHCR14B Blocking Peptide, LMN2R Blocking Peptide, MGC9041 Blocking Peptide, PHA Blocking Peptide, LBR Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
Lamin B Receptor (LBR)
Hintergrund
The protein encoded by this gene belongs to the ERG4/ERG24 family. It is localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.