A synthetic peptide for use as a blocking control in assays to test for specificity of ACE2 antibody, Alternative Names: ACE2 control peptide, ACE2 antibody Blocking Peptide, Anti-ACE2 Blocking Peptide, Angiotensin I Converting Enzyme Blocking Peptide, Peptidyl-Dipeptidase A 2 Blocking Peptide, ACEH Blocking Peptide, DKFZP434A014 Blocking Peptide
ACE2
Reaktivität: Human, Maus, Ratte
Wirt: Synthetic
BP
Applikationshinweise
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
ACE2
(Angiotensin I Converting Enzyme 2 (ACE2))
Hintergrund
ACE2 belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this geneuggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.