A synthetic peptide for use as a blocking control in assays to test for specificity of DISP1 antibody, Alternative Names: DISP1 control peptide, DISP1 antibody Blocking Peptide, Anti-DISP1 Blocking Peptide, Dispatched Homolog 1 Blocking Peptide, DISPA Blocking Peptide, DKFZP434I0428 Blocking Peptide, FLJ43740 Blocking Peptide, MGC104180 Blocking Peptide, MGC13130 Blocking Peptide, MGC16796 Blocking Peptide, DISP1, DISP-1, DISP 1, DISP-1 Blocking Peptide, DISP 1 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
DISP1
(Dispatched Homolog 1 (DISP1))
Hintergrund
DISP1 functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal. The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure.