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E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) Peptid

SIAH1 Reaktivität: Säugetier Wirt: Synthetic BP, IHC, WB
Produktnummer ABIN938472

Kurzübersicht für E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) Peptid (ABIN938472)

Target

SIAH1 (E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))

Spezies

Säugetier

Quelle

  • 5
Synthetic

Applikation

Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
  • Protein-Typ

    Synthetic

    Sequenz

    FTCLPAARTR KRKEMSRQTA TALPTGTSKC PPSQRVPALT GTTASNNDLA

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of SIAH1 antibody,
    Alternative Names: SIAH1 control peptide, SIAH1 antibody Blocking Peptide, Anti-SIAH1 Blocking Peptide, seven in absentia homolog 1, Drosophila Blocking Peptide, SIAH1, SIAH-1, SIAH 1, SIAH-1 Blocking Peptide, SIAH 1 Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    SIAH1 (E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))

    Hintergrund

    SIAH1 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

    Molekulargewicht

    35 kDa
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