A synthetic peptide for use as a blocking control in assays to test for specificity of SIAH1 antibody, Alternative Names: SIAH1 control peptide, SIAH1 antibody Blocking Peptide, Anti-SIAH1 Blocking Peptide, seven in absentia homolog 1, Drosophila Blocking Peptide, SIAH1, SIAH-1, SIAH 1, SIAH-1 Blocking Peptide, SIAH 1 Blocking Peptide
SIAH1
Reaktivität: Human, Ratte
Wirt: Synthetic
BP, BI
Applikationshinweise
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
SIAH1
(E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))
Hintergrund
SIAH1 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.