A synthetic peptide for use as a blocking control in assays to test for specificity of VNN2 antibody, Alternative Names: VNN2 control peptide, VNN2 antibody Blocking Peptide, Anti-VNN2 Blocking Peptide, vanin 2 Blocking Peptide, FOAP-4 Blocking Peptide, GPI-80 Blocking Peptide, VNN2, VNN-2, VNN 2, VNN-2 Blocking Peptide, VNN 2 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
VNN2
(Vanin 2 (VNN2))
Hintergrund
This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.