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Deoxynucleotidyltransferase, terminal (DNTT) Peptid

DNTT Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN938414

Kurzübersicht für Deoxynucleotidyltransferase, terminal (DNTT) Peptid (ABIN938414)

Target

TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Spezies

Säugetier

Quelle

  • 5
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    FQDLVVFILE KKMGTTRRAF LMELARRKGF RVENELSDSV THIVAENNSG

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of DNTT antibody,
    Alternative Names: DNTT control peptide, DNTT antibody Blocking Peptide, Anti-DNTT Blocking Peptide, Deoxynucleotidyltransferase Terminal Blocking Peptide, TDT Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

    Hintergrund

    DNTT is a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, DNTT is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor geneegments.

    Molekulargewicht

    58 kDa
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