A synthetic peptide for use as a blocking control in assays to test for specificity of COX3 antibody, Alternative Names: COX3 control peptide, COX3 antibody Blocking Peptide, Anti-COX3 Blocking Peptide, Cytochrome C Oxidase Iii Blocking Peptide, MTCO3 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
COX3 (COX-3)
(Cytochrome C Oxidase Subunit 3 (COX-3))
Hintergrund
COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency). Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.