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Chymase 1, Mast Cell (CMA1) Peptid

CMA1 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN938181
  • Target Alle CMA1 Produkte
    CMA1 (Chymase 1, Mast Cell (CMA1))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    EVKLRLMDPQ ACSHFRDFDH NLQLCVGNPR KTKSAFKGDS GGPLLCAGVA
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of CMA1 antibody,
    Alternative Names: CMA1 control peptide, CMA1 antibody Blocking Peptide, Anti-CMA1 Blocking Peptide, chymase 1, mast cell Blocking Peptide, CYH Blocking Peptide, MCT1 Blocking Peptide, MGC119890 Blocking Peptide, MGC119891 Blocking Peptide, chymase Blocking Peptide, CMA1, CMA-1, CMA 1, CMA-1 Blocking Peptide, CMA 1 Blocking Peptide
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    CMA1 (Chymase 1, Mast Cell (CMA1))
    Hintergrund
    CMA1 is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies.
    Molekulargewicht
    27 kDa
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