A synthetic peptide for use as a blocking control in assays to test for specificity of SPR antibody, Alternative Names: SPR control peptide, SPR antibody Blocking Peptide, Anti-SPR Blocking Peptide, sepiapterin reductase, 7,8-dihydrobiopterin:NADP+ oxidoreductase Blocking Peptide, SDR38C1 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
SPR
(Sepiapterin Reductase (SPR))
Hintergrund
This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.