Centromere Protein H (CENPH) Peptid
Kurzübersicht für Centromere Protein H (CENPH) Peptid (ABIN938137)
Target
Spezies
Quelle
Applikation
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Protein-Typ
- Synthetic
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Sequenz
- ESWDLEEKLL DIRKKRLQLK QASESKLLEI QTEKNKQKID LDSMENSERI
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of CENPH antibody,
Alternative Names: CENPH control peptide, CENPH antibody Blocking Peptide, Anti-CENPH Blocking Peptide, Centromere Protein H Blocking Peptide, NNF1 Blocking Peptide, PMF1 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- CENPH (Centromere Protein H (CENPH))
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Hintergrund
- Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. CENPH colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.
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Molekulargewicht
- 27 kDa
Target
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