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N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) Peptid

NECAB3 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN938135

Kurzübersicht für N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) Peptid (ABIN938135)

Target

NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

Spezies

Säugetier

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    ESVEAQSRLC GSRRAGRRAL RSVSRSSTWS PGSSDTGRSS EAEMQWRLQV

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of NECAB3 antibody,
    Alternative Names: NECAB3 control peptide, NECAB3 antibody Blocking Peptide, Anti-NECAB3 Blocking Peptide, N-Terminal Ef-Hand Calcium Binding Protein 3 Blocking Peptide, APBA2BP Blocking Peptide, EFCBP3 Blocking Peptide, NIP1 Blocking Peptide, STIP3 Blocking Peptide, SYTIP2 Blocking Peptide, XB51 Blocking Peptide, dJ63M2.4 Blocking Peptide, dJ63M2.5 Blocking Peptide, NECAB3, NECAB-3, NECAB 3, NECAB-3 Blocking Peptide, NECAB 3 Blocking Peptide

    Aufreinigung

    The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

    Hintergrund

    The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

    Molekulargewicht

    44 kDa
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