A synthetic peptide for use as a blocking control in assays to test for specificity of AKAP10 antibody, Alternative Names: AKAP10 control peptide, AKAP10 antibody Blocking Peptide, Anti-AKAP10 Blocking Peptide, A-kinase anchoring protein 10 Blocking Peptide, Prka Anchor Protein 10 Blocking Peptide, AKAP Blocking Peptide, D-AKAP2 Blocking Peptide, MGC9414 Blocking Peptide, PRKA10 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
AKAP10
(A Kinase (PRKA) Anchor Protein 10 (AKAP10))
Hintergrund
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA, therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.